About Me

Name : Sung Kwang LEE

EDUCATION

Mar. 2000 – Aug. 2000 : Post-doctor, CAMD Research Center, Soong Sil Univ.
Mar. 1995 – Feb. 2000 : Dept. of Chemistry, Yonsei University Ph.D (Major : Analytical Chemistry)
- Thesis: Quantitative Relationships between Retention Behavior and Molecular Structure of Organic compounds in Reversed Phase Liquid Chromatography
Mar. 1993 – Feb. 1995 : Dept. of Chemistry, Yonsei University M.S. (Major : Analytical Chemistry)
Thesis:Preconcentration and Determination of Trace Organic Pollutants by Solid Phase Extraction-HPLC On-Line System
Mar. 1989 – Feb. 1993 : Dept. of Chemistry, Yonsei University B.S. (Major : Chemistry)

EXPERIENCES

Sep. 2022 – Feb.2024 : Dean of Office of Career Development and Start-up Support, Hannam University
Sep. 2022 – Feb.2024 : Director of Business Startup Support Office, Hannam University
Mar. 2020 – Feb.2022 : Dean of Academic Information Affairs, Hannam University
Apr. 2018 – present : Professor, Department of Chemistry, Hannam University
Mar. 2013 – Mar. 2018: Associate Professor, Department of Chemistry, Hannam University
Mar. 2014 – Feb. 2015 : Director, Technology Licensing Office, Industry-Academia Cooperation Foundation, Hannam University
Sep. 2013 – Dec. 2014 : Member of Advisory Committee, Chemical Safety Support commitee, Geumgang Basin Environment Agency
Mar. 2009 – Feb. 2013 : Assistant Professor, Department of Chemistry, Hannam University.
Aug. 2002 – Feb. 2009: Head, Chem & Bioinformatics software development division, Bioinformatics & Molecular Design Research Center (BMDRC)
Mar. 2007 – Aug. 2007:Lecturer(Drug design), Colledge of Pharmacy, SookmyungWoman Univ.
Mar. 2006 – Aug. 2006: Lecturer(Cheminformatics), Dept. of Biomedical technology, Sangmyung Univ.
Sep. 2005 – Nov. 2005: Member of Advisory Committee in technology of risk assessment, Korea FDA
Feb. 2004 – Feb. 2005: Visting Scientist, Prof. Gasteiger group – Computer Chemistry Center, Univ. Erlangen-Nuerenburg, Germany
Jan. 2003 – Jan. 2004: Cheminformatics Executive Secretary, Korean Society for Bioinformatics
Aug. 2002 – Jan. 2003: Member of Advisory Committee in Bioinformation generation/ archiving technology, National Technology Roadmap, MOST
May 2001 – Dec. 2001: Member of Advisory Committee in Bioinformatics, Korea Research Council of Fundamental Science & Technology
Sep. 2000 – Aug. 2002: Senior Researcher, CAMD Research Center, Soong Sil Univ.
Mar. 1998 – Feb. 1999: Computer Teaching and Assistant, Department of Chemistry, Yonsei University
Mar. 1995 – Aug. 1996:Lecturer(Advanced Analytical Chemistry), Department of Chemistry, Yonsei University
Mar. 1993 – Feb. 2000: Researcher, Institute of Natural Science, Yonsei University
Mar. 1993 – Feb. 1997: Teaching and Research Assistant, Department of Chemistry, Yonsei University

RESEARCH AREA

Analytical chemistry
- Retention mechanism and retention behavior – Using Quantitative structure-retention relationships(QSRRs)
- HPLC optimization – Experimental Design, Overlapping Resolution Maps(ORM)
- Sample pretreatment – Solvent Extration, Solid Phase Extraction(SPE), Development of On-line, off-line SPE-HPLC system, Supercritical Fluid Extration(SFE)
Chemoinformatics
- Development of QSAR & QSPR model
- Chemical DB design & structure similarity search
- Chemical library design considering molecular diversity, ADME/Tox and Deconvolution
- in silico ADME/Tox prediction
- Physicochemical properties prediction
- Development of data mining algorithm (ensemble model, deep learning, generic algorithm)
- Virtual screening (pharmacophore search, docking)

DEVELOPED SYSTEMS

ChemDB (web-based chemical database)
CMiB DB (web-based polymer and chemical material database)
KTKP compound DB (major compounds db in Korean Traditional Knowledge Portal)
PreADMET(web-based ADME prediction program)
MS-HEMs (Management System for High Energy Molecules)
Topomol (molecular descriptors calculator)
Substrucgen (exact and substructure searching program using subgraph isomorphism)
Simstrucgen (similarity searching program using molecular structure keys and properties)
HOFGen v 1.0 (Heat of formation calculation program)
DensityGen v1.0 (Crystal density calculation program)
Div_set (data spliting program using sphere exclusion algorithm)
NN_opt3 (neural net program using Resilient back-propagation algorithm)
Category classifier (classification system of toxicity categories for hazard assessment)
HEMbrowser (High Energy Molecules Database and Predictor)
IHToxPre (inhalation toxicity database and predictor)
ImmunoToxPre (immunotoxicity database and predictor)

PROJECTS

약물 대사, 투과 및 심장독성 예측모델 고도화– ㈜파로스아이바이오 (2023.7– 2024..6)
신약개발을 위한 ADME물성 예측모델 고도화 – ㈜파로스아이바이오 (2022.3.1 – 2023.2.28)
인공지능 기술을 활용한 약물-키나아제 단백질 상호작용 예측모델 개발 – LINC 3.0 산학연협력선도대학육성사업 (2022.10-2023.1)
K-water 자체 수질안전 평가지수 핵심 기술개발 용역과제 (2022.1-2022.12), 한국수자원공사-서울녹생환경지원센터
면역세포 등을 이용한 면역독성 평가기술 개발연구 – 면역독성 예측을 위한 in silico QSAR모델 개발(2020.2-2021.12), 식품의약품안전평가원
열 및 전기특성 플라시특 복합수지의 빅데이터구축과 인공지능기술을 활용한 정확도 90%이상의 조성,물성예측 및 용도 추천 플랫폼 개발(2018.7-2022.12), 산업기술평가관리원
In vitro 시스템을 이용한 호흡기계 독성 검색시험법 사전검증 연구(2018.2-2019.11), 식품의약품안전처
In vitro 호흡기계 독성예측 시스템 개발 연구 용역과제(2016.3-2017.11),식품의약품안전처
원(연) 중저준위 방사성폐기물 핵종농도 예측방법 개발 용역과제 (2014.5-2015.12), 한국원자력연구원
‘데이터분석 산학융합연구실’ 2013년 교육부 산업단지캠퍼스 조성사업 산학융합연구실사업 (2013.7-2014.6) 한남대학교 산업단지캠퍼스 사업단
‘특수기능화합물 승화열, 발화점 예측 모델 개발’ 민군겸용기술사업 용역과제 (2013.6-2015.5), (주)이큐스앤자루 신약개발연구소
‘에너지물질 변환특성 설계기법 연구’ 차세대 융복합 에너지 물질 특화연구센터 과제 (2012.9-2017.12), 방위산업청/국방과학연구소
‘잔류성 유기오염물질의 수계 이동특성 예측을 위한 QSAR모델 및 물성예측 시스템 개발’ 한국연구재단 일반연구자지원사업 (2012.4-2015.4)
‘카테고리화 방식에 의한 화학물질 평가방안 마련’ (2012.4-2012.11), 국립환경과학원 용역과제
‘저탄소 고에너지물질의 분자설명인자 및 분해특성물 계산’ (2011.9-2011.12), 국방과학연구소 용역과제
‘화약물질의 생성열 예측을 위한 프로그램 보정’ (2010.6-2011.12) (사)분자설계연구소 용역과제
‘실리콘 전구체 개발’ (2010.4-2010.6), (주)유엠티 기업용역과제
‘잔류성 환경유기오염물질의 대기중 반감기 예측 및 유해성 우선순위 결정을 위한 QSAR예측’, (2010.4-2011.3), 한국연구재단 일반연구자 신진연구지원사업.
‘CVD 성능향상을 위한 Si-precursor 성능개선 모델제시’ (2008.11-2009.1), 유니온머트리얼텍 기업용역과제.
‘유전독성과 발암성 예측 지표 마커와 모델 검증 연구’ (2008.3-2008.11), 식품의약품안전청 국립독성연구원 / 이화여자대학교
‘화학소재 데이터베이스 및 정보시스템 구축’ (2008.1-2008.5), 한국화학연구원 화학소재정보은행
‘특허 화합물 색인 및 약용물질 분석시스템 개발’ (2007.5-2007.11), 한국과학기술정보연구원(KISTI) 용역과제.
‘화학구조 데이터베이스를 활용한 바이오제틱 아민류의 구조유사성 관계 활용’ (2007.7-2007.11), 식품의약품안전청 국립독성연구원 용역과제
‘ADME/Tox 예측을 위한 가상신약 기술 개발’ (2006.12-2007.9), 한국산업기술평가원/ (주)이쿠스팜신약개발연구소
‘전통지식 DB구축 관련 성분화합물 DB구축’ (2006.7-2006.12), 한국과학기술정보연구원/한국한의학연구원 용역과제.
‘유해물질의 위해성평가를 위한 QSARs연구’ (2006.5-2006.11), 식품의약품안전청 용역연구사업.
‘위탁기술개발 과제명 : 지능형 독성예측 시스템 개발’ 바이오소재 발굴을 위한 유전체DB 분석시스템 개발’ (2003.9-2006.8), 산업자원부 중기거점/차세대신기술개발 사업 위탁과제.
‘구조활성상관관계(QSAR)을 활용한 농약의 구조 유사성 예측 프로그램 개발’ (2005.10-2005.11), 식품의약품안전청 국립독성연구원 용역과제
‘신약개발을 위한 화합물DB’, 과학기술 및 산업기술 첨단정보 DB 구축사업 (2000.1-2001.1, 2002.1-2005.11), 한국과학기술정보연구원 용역과제

PUBLICATIONS

I.H. Song, D.R. Shin, S.K. Lee “Feature selection of QSAR model according to several feature importances”, 2024, submitting.
D.R. Shin, W.J. Choi, N.J. Cho, S.K. Lee “Prediction of volume resistivity of polymer composites using ensemble models with featue generation”, 2024, submitting.
S.-H. Park, H.-G.Lee, X. Liu, S.K.Lee*, and Y.-T.Change*, “Quantitative Structure-Activity Relationship of Fluorescent Probes and Their Intracellular Localizations”, Chemosensors, 2023,11, 310.
H. Quan, H.Jun, K.Kim, S.K.Lee, Y. Heo, S.H.Seok, Y.R.Na, “Development of a transcriptome‑based determination of innate immune suppressor (TDIS) assay as an in vitro test for immunotoxicity”, Arch. Toxicol., 2023, 97, 495-507.
J.H.Shin, B.H.Lee, S.K.Lee “Development of QSAR Models for Subchronic Inhalation Toxicity Using Random Forest Regression Method”, Bull. Korean, Chem. Soc., 2019, 40, 819-825.
H.J.Kim, B.H.Lee, S.G.Cho, S.K.Lee “Comparative analysis of detonation velocity in determining product composition for high energetic molecules using stoichiometric rules” Anal. Sci. Technol. 2017, 30(6), 405-410.
M.H.Kim, B.Lee, N.Kim, M.Shin, H.J.Shin, K. Kwon, J.S.Kim, S.K.Lee, Y.G.Kim “Bis(dinitropyrazolyl)methanes as Stable High Energy Materials”, Bull. Korean Chem. Soc., 2017, 38, 751-755.
K.-W. Kim, Y.L.Won, D.J.Park, Y.S.Kim, E.S.Jin, S.K.Lee “Combined Toxic Effects of Polar and Nonpolar Chemicals on Human Hepatocytes (HepG2) Cells by Quantitative Property – Activity Relationship Modeling” Toxicol. Res. 2016, 32, 347-345.
Y.S.Park, J.H.Lee, H.W.Park, S.K.Lee”QSPR analysis for predicting heat of sublimation of organic compounds” Anal. Sci. Technol. 2015, 28(3), 187-195.
K.-W.Kim, Y.L.Won, K.S.Ko, Y.J.Choi, S.K.Lee “PCDDs and DFs concentration from the fly ash and bottom ash of industrial wast incinerators in Korea” Anal. Sci. Technol. 2014, 27(6), 347-351.
K.-W. Kim, S.Park, Y.L.Won, S.K.Lee “Effects of low-level exposure to manganese and lead on immune function“, Anal. Sci. Technol., 2014,27(5),248-253.
K.-W.Kim, Y.L.Won, M.K.Hong, J.H.Ju, S.K.Lee “Prediction of mixture toxicity of dimethylformamide, methyl ethyl keton and toluene by QSAR” Bull. Korean Chem. Soc., 2014, 35(12), 3637-3641.
D.Kim, S.Park, Y.Choi, S.K.Lee “Optimization of solvent for the determination of polybrominated diphenyl ethers in high-impact polystyrene by GC/ECD“, Bull. Korean Chem. Soc., 2012, 33(10), 3485-3488.
S.K.Lee, S.G.Cho, J.S.Park, K.Y.Kim, K.T.No “MS-HEMs: An on-line Management Systems for High-Energy Molecules at ADD and BMDRC in Korea“, Bull. Korean Chem. Soc., 2012, 33(3), 855-861.
Y.In, S.K.Lee, P.J.Kim, K.T.No “Prediction of Acute Toxicity to Fathead Minnow by Local Model Based QSAR and Global QSAR Approaches”, Bull. Korean Chem. Soc., 2012, 33(2), 613-619.
I.S.Song, J.Y.Cha, S.K.Lee, “Prediction and analysis of acute fish toxicity of pesticides to the rainbow trout using 2D-QSAR“, Anal. Sci. Technol., 2011, 24(6), 544-555.
E.H.Jeon, J.H.Park, J.H.Jeong, S.K.Lee, “2D-QSAR analysis for hERG ion channel inhibitors“, Anal. Sci. Technol., 2011, 24(6), 533-543.
S.K.Lee, “On-line SPE-HPLC method using alumina filtering to selectively extract phenolic compounds from environmental water“, Bull. Korean Chem. Soc., 2010,31(12), 3755-3759.
S.Lee, S.T.Kim, B.R.Pant, H.D.Kwen, H.H.Song, S.K.Lee, S.V.Nehete “Carboxymethylation of corn starch and characterization using asymmetrical flow field-flow fractionation coupled with multi angle light scattering” J. Chromatogr. A, 2010, 1217, 4623.
S.Lee, T.W.Lee, S.K.Cho, S.T.Kim, D.Y.Kang, H.D.Kwen, S.K.Lee, C.H.Eum“Implementation of splitter-less SPLITT fractionation and its application to large scale-fractionation of sea sediment” Microchem. J., 2010, 95, 11-19.
S.Lee, H.D.Kwen, S.K.Lee, S.V.Nehete, “Study on elution behavior of poly (amidoamine) dendrimers and their interaction with bovine serum albumin in asymmetrical flow field-flow fractionation“, Anal. Bioanal. Chem., 2010, 396,1581-1588.
D.N.Kim, K.-H.Cho, W.S.Oh, C.J.Lee, S.K.Lee, J.Jung and K.T.No “E_aMEAD: Activation Energy Prediction of Cytochrome P450 Mediated Metabolism with Effective Atomic Descriptors“, J. Chem. Inf. Modeling, 2009, 49(7), 1643-1654.
H.An, S.-J.Eum, M.Koh, S.K.Lee, S.B.Park, “Diversity-oriented Synthesis of Privileged Benzopyranyl Heterocycles with Diversity in Polar Surface Charge” J. Org. Chem., 2008, 73, 1752-1761.
C.Keum, S.K.Lee, K.T.No “Clustering public microarray data in GEO according to experiment condition”, Proceedings of the 8th International Conference of Korean Society for Bioinformatics, 2007, pp92-100.
Y.E.Kwon, J.Y.Park, K.T.No, J.H.Shin, S.K.Lee, J.S.Eun, J.H.Yang, T.Y.Shin, D.K.Kim, B.S.Chae, J.-Y.Leem, K.H.Kim, “Synthesis, in vitro assay, and molecular modeling of new piperidine derivatives having dual inhibitory potency against acetylcholinesterase and Aβ1–42 aggregation for Alzheimer’s disease therapeutics”, Bioorg. Med. Chem., 2007, 15(20), 6596-6607.
S.K.Lee, K.T.No “In Silico approach for predection of in vitro chromosomal aberration and in vivo micronucleus analysis”, Proceedings of Asia Hub for e-Drug Discovery (AHeDD) Symposium 2007, p 33.
H.Kim, S.K.Lee, J.H.Shin, K.-Y.Nam, J.Kwak, J.H.Yoon, K.T.No “Introduction of Integrated e-Drug Discovery System, Lead Explore”, Proceedings of Asia Hub for e-Drug Discovery (AHeDD) Symposium 2007, p9.
S.K.Lee, G.S.Chang, Y.In, K.T.No “Prediction of rodent carcinogenicity of Structurally diverse compounds using several machine learning methods”, Proceedings of QSAR 2006 International Symposium in Environmental Toxicology, 2006, p109.
Y.In, S.Park, S.K.Lee, K.T.No “A recursive-partitioning model for acute fish toxicity”, Proceedings of QSAR 2006 International Symposium in Environmental Toxicology, 2006, p142.
S.K.Lee, “In Silico High-throughput Screening for ADME/Tox Properties:PreADMET Program“, Proceedings of 21st Conference on Combinatorial Chemistry, 2005, 22-28.
S.K.Lee, I.H.Lee, H.J.Kim, G.S.Chang, J.E.Chung, K.T.No, “”PreADME approach: Web-based program for rapid prediction of physicochemical, drug absorption and drug-like properties”, The 14th EuroQSAR 2002: Designing Drugs and Crop Protectants: processes, problems and solutions, 2003, pp. 418-420. Blackwell Publishing, Massachusetts, USA
W.-S.Kim, J.Y.Lee, S.K.Lee, Y.H.Park, D.W.Lee “Investigation of Retention Behavior for Herbicides in Micro-HPLC with Temparature Changes“, J. Liq. Chrom & Rel. Technol. 2003, 26(20), 3357-3369.
S.K.Lee, K.T.No ” In silico ADME and pharmacokinetics”, Bioindustry, 2002, 15(5), 16-19.
Y.S.Kim, S.K.Lee, J.H.Kim, J.S.Kim, K.T.No “Prediction of Autoignition Temperatures(AITs) for Hydrocarbons and compounds contaiining heteroatoms by Quantittive Structure-Property Relationships” J. Chem. Soc. Perkin Trans.II, 2002, 12, 2087-2092.
D.-H.Kim, S.K.Lee, W.S.Kim, J.S.Yang, D.W.Lee, “Quantitative Retention Activity Relationship of Quinolones Using Micellar Liquid Chromatography” J. Liq. Chrom & Rel. Technol. 2001, 24(9), 1309-1322.
S.K.Lee, K.T.No, “Organic Chemical Database for Drug Design” Journal of Scienific & Technological Knowledge Infrastructure, 2001, 6, 41-50.
D.H.Cho, S.K.Lee, B.T.Kim, K.T.No, “Quantitative Structure-Activity Relationship(QSAR) Study of New Fluorovinyloxyacetamides” Bull. Korean Chem. Soc. 2001, 22(4), 388-394.
C.K.Byun, J.H.Song, S.K.Lee, D.H.Kim, D.W.Lee, ” Salt Effects on the Retention of Peptides in Hydrophobic Interaction Chromatography” J. Liq. Chrom & Rel. Technol. 2000, 23(19), 2963-2978.
D.-H.Kim, S.K.Lee, Y.H.Park, D.W.Lee, “High Performance Liquid Chromatographic Determination of Ciprofloxacin and its Metabolites in Urine” J. Liq. Chrom & Rel. Technol. 2000, 23, 1069-1081.
S.K.Lee, K.T.No, “Cheminformatics for drug design” Journal of Scienific & Technological Knowledge Infrastructure, 2000, 10, 68-75.
S.-H.Lee, S.K.Lee, Y.H.Park, H.J.Kim, D.W.Lee “Preconcentration and Detection of Herbicides in Water Using On-line SPE-HPLC system and Photochemical Reaction” Bull. Korean Chem. Soc. 1999, 20(10), 1165-1171.
J.S.Yang, S.K.Lee, Y.H.Park, D.W.Lee “Analytical Method for Dioxin and Organo-Chlorinated Compounds: (Ⅱ) Comparison of Extraction Methods of Dioxins from XAD-2 Adsorbent”, Bull. Korean Chem. Soc. 1999, 20(6), 689-695.
S.K.Lee, Y.H.Park, C.J.Yoon, D.W.Lee, “Investigation of Relationships Between Retention Behavior and Molecular Descriptors of Quinolones in PRP-1 Column“, J. Microcol. Sepn., 1998, 10(1), 133-139.
H.S. Kim, S.K. Lee, D.W.Lee, ” Study of Retention Behavior of Pesticides for Reversed Phase Liquid Chromatographic Separation by Quantitative Structure-Retention Relationships“, J. Liq. Chrom & Rel. Technol., 1997, 20(6), 871-885.
D.W.Lee, S.K.Lee, Y.H.Park, K.-J.Paeng. ” Determination of Pesticide Residues in Water using On-line SPE-HPLC Coupling System”, Anal. Sci. & Technol., 1995, 8(4), 539-543.

PATENTS & SOFTWARES

키나아제 억제제-암 세포주 반응 예측프로그램, 등록번호: C-2023-008845, Korea Copyright Commission, 2023.2.22.
고분자 복합소재 물성 예측 프로그램, 등록번호 : C-2023-031194, Korea Copyright Commission, 2023.7.25.
“염 에너지물질의 밀도 예측 QSPR방법” Reg:10-1960514/5m, S.K,Cho, E.S.Jin, H.J.Kim, M.J.Lee, S.K.Lee, Korean intellectual property office, 2019.3.20.
“유기화합물의 생물농축인자를 예측하는 QSPR방법” Reg:10-1792653, S.K.Lee, J.H.Jung, E.S.Jin, Youn, H.J.Kim, J.H.Lee, H.U.Park Korean intellectural property office, 2017.10.26.
“유기화합물의 승화열을 예측하는 QSPR방법” Reg:10-1765114, U.S.Park, S.K.Lee, J.H.Youn, H.J.Kim, Korean intellectural property office, 2017.7.31.
“유기화합물의 자연발화온도를 예측하는 QSPR방법” Reg:10-1754722, M.Y.Jung, S.K.Lee, J.H.Youn, H.J.Kim, J.H.Lee, H.U.Park Korean intellectural property office, 2017.6.30.
“고에너지 고체 화합물의 생성열을 예측하는 QSPR방법” Reg:10-1610741, Seong Eun Shin, Soo Gyeong Cho, Sung Kwang Lee, Korean intellectural property office, 2016.4.4.
“고에너지 화합물의 밀도를 예측하는 QSPR방법” Reg:10-1610743, Si Nae Hwang, Soo Gyeong Cho, Sung Kwang Lee, Korean intellectural property office, 2016.4.4.
“고에너지 화합물의 충격감도를 예측하는 QSPR방법” Reg:10-1610340, Ji Young Lee, Soo Gyeong Cho, Sung Kwang Lee, Korean intellectural property office, 2016.3.11.
“Method for predicting activation energy using an atomci fingerprint desciptor or an atomci descriptor” Reg: US 2011/0213558 A1, Ky Youb Nam, Kyoung Tai No, Doo Nam Kim, Won Seok Oh, Sung Kwang Lee, Ji Hoon Jung, Kwang Hwi Cho, Chang Joon Lee, US Patent Application, Sep. 1, 2011.
“최단경로행렬을 이용한 최소길이의 폐구간을 이루는 노드들을 검출하는 프로그램이 저장된 매체”, Reg:10-1047429, Kyoung Tai No, Chang Joon Lee, Kwang Hwi Cho, Sung Kwang Lee, Jae Seong Park, Korean intellectural property office, 2011.7.1.
“Media storing a program of detecting nodes which consist the closed path of the shortest distance using an adjacency matrix”, Reg:10-0920966, Kyoung Tai No, Chang Joon Lee, Kwang Hwi Cho, Jae Seong Park, Sung Kwang Lee, Korean intellectural property office, 2009.10.1.
“DensityGen v 1.0 – Prediction program for crystal density of organic compounds” Reg:2009-01-129-003873,BMDRC,Korea Software Copyright Committe, 2009.7.29.
“HOFGen v 1.0 – Prediction program for heat of formation” Reg:2009-01-129-003848,BMDRC,Korea Software Copyright Committe, 2009.7.29.
“MS-HEMs – Manegement system for high energy molecules” Reg:2009-01-129-003837,BMDRC,Korea Software Copyright Committe, 2009.7.29.
“PreADMET ver 2.0 -Prediction program for ADME/Tox properties”Reg:2007-01-121-007356, Sung Kwang Lee,Se Ho Park, In Hye Lee, Kyoung Tai No, BMDRC,Korea Software Copyright Committe, 2007.12.14.
“X3Dmole – 3D chemical viewer program”, Reg:2007-01-129-007209, BMDRC, Korea Software Copyright Committe, 2007.12.10.
“DBdrawX v1.0 – 2D chemical drawer program”, Reg:2007-01-129-007210, BMDRC, Korea Software Copyright Committe, 2007.12.10.
“EnTox Gov ver 1.0 – prediction program for acute fish toxicity”, Reg:2007-01-129-000483, BMDRC, Korea Software Copyright Committe, 2007.1.15.
“PreADME v1.0, Prediction program for ADME properties” Reg:2004-01-120-002495, BMDRC, Korea Software Copyright Committe, 2004.5.4

BOOK

Sung Kwang Lee, et al, “Rouessac – Chemical Analysis” 6ed., 2009.
Sung Kwang Lee, Youngyong In, In Hye Lee, Se Ho Park, Jae Seong Park,
Doo Nam Kim, “PreADMET ver 2.0 : user manual”, 2007.
Sung Kwang Lee, Gue Su Chang, In Hye Lee, “PreADME : user manual, Theory and tutorial” 2004.
Sung Kwang Lee, Il Hie Lee “Molecular Modeling Using CAChe Program, Molecular Design by Chemistry” CAChe Tutorial, 1998.